SCHEMBL26348105

SCHEMBL26348105

CC(O)(C(=O)O)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
PDK1 Q15118 6/20 0.36
PDK2 Q15119 6/20 0.36
PDK3 Q15120 6/20 0.36
PDK4 Q16654 6/20 0.36
TET2 Q6N021 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
ACLY P53396 2/20 0.31
ABCC9 O60706 2/20 0.31
ABCC8 Q09428 2/20 0.31
KCNJ11 Q14654 2/20 0.31
KCNJ8 Q15842 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26348102 0.90 THRB (0.54) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL569205 0.85 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL568924 0.85 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL568925 0.85 ALDH1A1 (0.53) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL18562452 0.77 ALDH1A1 (0.50) THRBALDH1A1TSHRPDK1PDK2
SCHEMBL606619 0.75 ALDH1A1 (0.64) ALDH1A1TSHRPDK1PDK2PDK3
SCHEMBL10472538 0.75 ALDH1A1 (0.64) ALDH1A1TSHRPDK1PDK2PDK3
SCHEMBL10453248 0.75 ALDH1A1 (0.64) ALDH1A1TSHRPDK1PDK2PDK3
SCHEMBL28371881 0.74 THRB (0.48) THRBALDH1A1TSHRCYP2D6CYP2C19
SCHEMBL26348120 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230305398-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed