SCHEMBL26348118

SCHEMBL26348118

CCCC(O)(C(=O)O)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.47
ACLY P53396 2/20 0.41
FDPS P14324 1/20 0.34
POLB P06746 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CES2 O00748 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
KDM4C Q9H3R0 1/20 0.32
FAAH O00519 5/20 0.32
CES1 P23141 3/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10932999 0.86 TET2 (0.44) TET2ACLYCES2FAAHCES1
SCHEMBL3615665 0.85 ALDH1A1 (0.40) TET2ACLYFDPSALDH1A1TSHR
SCHEMBL1000252 0.80 TET2 (0.50) TET2ACLYPOLBNPSR1ALDH1A1
SCHEMBL1000250 0.80 TET2 (0.50) TET2ACLYPOLBNPSR1ALDH1A1
SCHEMBL7823505 0.74
SCHEMBL5748868 0.74
SCHEMBL8513159 0.73 CES2 (0.34) FDPSCES2ALDH1A1FAAHCES1
SCHEMBL15362566 0.73 CES2 (0.34) FDPSCES2ALDH1A1FAAHCES1
SCHEMBL2484704 0.73 FDPS (0.32) ACLYFDPSALDH1A1TSHR
SCHEMBL28220010 0.73 TET2 (0.44) TET2ACLYPOLBNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230305398-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
CN-116670140-A Macrocyclic compounds containing 1,3, 4-oxadiazole rings as modulators of cystic fibrosis transmembrane conductance regulator 弗特克斯药品有限公司 2023-08-29 CN disclosed