SCHEMBL26349625

SCHEMBL26349625

CC[C@H]1OC(OCc2ccccc2)[C@H](NC(=O)CCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)[C@@H](OCc2ccccc2)[C@@H]1C

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ SSTR3 P32745 4/20 0.38
▸ SSTR5 P35346 4/20 0.38
▸ SSTR2 P30874 2/20 0.38
▸ SSTR1 P30872 1/20 0.38
▸ SSTR4 P31391 1/20 0.38
▸ STS P08842 1/20 0.37
▸ THRB P10828 2/20 0.36
▸ LMNA P02545 2/20 0.36
▸ YAP1 P46937 1/20 0.36
▸ MCHR1 Q99705 3/20 0.36
▸ GAA P10253 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ KLK7 P49862 1/20 0.36
▸ SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26349638 0.81 SSTR3 (0.41) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL29410615 0.77 SSTR3 (0.41) L3MBTL1SSTR3SSTR5SSTR2SSTR1
SCHEMBL29410617 0.76 PTPN1 (0.42) L3MBTL1
SCHEMBL15143128 0.76 L3MBTL1 (0.50) L3MBTL1SSTR3SSTR5SSTR2SSTR1
SCHEMBL30530241 0.75 SSTR3 (0.41) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL15504386 0.71 L3MBTL1 (0.41) L3MBTL1KLK7
SCHEMBL26878507 0.71 LMNA (0.45) L3MBTL1SSTR3SSTR5SSTR2SSTR1
SCHEMBL21058342 0.69 SSTR3 (0.48) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL26349670 0.69 NPC1 (0.40) SMN1; SMN2
SCHEMBL15087298 0.68 L3MBTL1 (0.39) L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF REYOUNG CORPORATION (US) 2023-09-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF TLR9, XIAP, ENPP2 GPR119 821/4885L3MBTL1 1782/4885SSTR3 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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