SCHEMBL26349638

SCHEMBL26349638

C[C@H]1[C@H](OCc2ccccc2)[C@@H](NC(=O)CCC(=O)N2CCNCC2)C(OCc2ccccc2)O[C@@H]1CO

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SSTR3 P32745 5/20 0.41
▸ SSTR5 P35346 5/20 0.41
▸ SSTR2 P30874 3/20 0.41
▸ SSTR1 P30872 1/20 0.41
▸ SSTR4 P31391 1/20 0.41
▸ MCHR1 Q99705 12/20 0.38
▸ LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530241 0.92 SSTR3 (0.41) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL29410615 0.84 SSTR3 (0.41) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL26349625 0.81 GPR119 (0.39) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL26349664 0.81 TNF (0.39) —
SCHEMBL21058342 0.76 SSTR3 (0.48) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL29410626 0.74 PTPN1 (0.43) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL21058364 0.74 SSTR3 (0.55) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL26349670 0.71 NPC1 (0.40) —
SCHEMBL15143128 0.71 L3MBTL1 (0.50) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL16076881 0.71 SLC6A2 (0.48) SSTR3SSTR5SSTR2SSTR1SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF REYOUNG CORPORATION (US) 2023-09-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303618-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF TLR9, XIAP, ENPP2 SSTR3 3941/4885SSTR5 2945/4885SSTR2 3807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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