SCHEMBL263555

SCHEMBL263555

C=C(C)CON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24153334 0.82 KMT2A (0.34) ALOX12KMT2AATMKDM4EPOLB
SCHEMBL13479718 0.81 ALOX12 (0.37) ALOX12KMT2AATMKDM4EPOLB
SCHEMBL16340691 0.79 POLB (0.42) KMT2APOLBLMNASMN1; SMN2MAPT
SCHEMBL17903314 0.77 ALOX12 (0.46) ALOX12KMT2AATMKDM4EPOLB
SCHEMBL24152404 0.76 ALOX12 (0.34) ALOX12SMN1; SMN2MAPT
SCHEMBL9516281 0.75 ALDH1A1 (0.33) LMNAMAPT
SCHEMBL28933285 0.74 ALOX12 (0.42) ALOX12KMT2AATMKDM4EPOLB
SCHEMBL14387773 0.71 KMT2A (0.36) KMT2AATMGLA
SCHEMBL18969713 0.71 ALOX12 (0.36) ALOX12KMT2AKDM4EPOLBSMN1; SMN2
SCHEMBL11339328 0.70 ALOX12 (0.41) ALOX12KDM4EPOLBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085317-A Reactive UCST copolymer and preparation method thereof 中国医学科学院生物医学工程研究所 2022-02-25 CN claimed
US-10369227-B2 Immunocompatible polymers MCMASTER UNIVERSITY (CA) 2019-08-06 US claimed
US-20140309313-A1 IMMUNOCOMPATIBLE POLYMERS MCMASTER UNIVERSITY (CA) 2014-10-16 US claimed
US-8815283-B2 Immuno-compatible hydrogel system MCMASTER UNIVERSITY (CA) 2014-08-26 US claimed
US-20130177976-A1 COMBINATION OF CATIONIC POLYMERS AND POLYSACCHARIDES NANOPARTICLES AS A GENE CARRIER KAOHSIUNG MEDICAL UNIVERSITY (TW) 2013-07-11 US claimed
US-20130136714-A1 FUNCTIONALIZED POLYMER NANOPARTICLES AND THE PHARMACEUTICAL USE THEREOF KAOHSIUNG MEDICAL UNIVERSITY (TW) 2013-05-30 US claimed
US-20120107394-A1 IMMUNO-COMPATIBLE HYDROGEL SYSTEM MCMASTER UNIVERSITY (CA) 2012-05-03 US claimed
EP-2438115-A1 IMMUNO-COMPATIBLE HYDROGEL SYSTEM Stover, Harald (CA) 2012-04-11 EP claimed
US-8133411-B2 Fluorescent polymers soluble in an aqueous solution and a method for the production thereof BIOMERIEUX S.A. (FR) 2012-03-13 US claimed
WO-2010139061-A1 IMMUNO-COMPATIBLE HYDROGEL SYSTEM STOVER HARALD (CA) 2010-12-09 WO claimed
EP-1701741-A2 COMPLEXES HAVING ADJUVANT ACTIVITY Polytherics Limited (GB) 2006-09-20 EP claimed
US-7071265-B2 Copolymerization of N-acryloxysuccinimide or N-methacryloxy-succinimide with methyl methacrylate, in the presence activators, solvents and stabilizer agents to form narrow particle size distribution copolymers FUJI XEROX CO., LTD. (JP) 2006-07-04 US claimed
EP-1290052-B1 BIOCOMPATIBLE POLYMER FOR FIXING BIOLOGICAL LIGANDS BIO MERIEUX (FR) 2006-05-03 EP claimed
US-6969742-B2 Method of producing a functional polymer particle FUJI XEROX CO., LTD. (JP) 2005-11-29 US claimed
WO-2005065712-A2 COMPLEXES HAVING ADJUVANT ACTIVITY POLYTHERICS LIMITED (GB) 2005-07-21 WO claimed
US-6914100-B2 Method of producing a crosslinked polymer particle FUJI XEROX, CO., LTD. (JP) 2005-07-05 US claimed
US-20040091451-A1 Biocompatible polymer for fixing biological ligands BIO MERIEUX (FR) 2004-05-13 US claimed
US-20040039109-A1 Method of producing a functional polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-26 US claimed
US-20040034171-A1 Method of producing a non-crosslinked polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-19 US claimed
US-20040034174-A1 Method of producing a crosslinked polymer particle FUJI XEROX CO., LTD. (JP) 2004-02-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040091451-A1 Biocompatible polymer for fixing biological ligands CD40, FCGR1A, CD47 ALOX12 3551/4885KMT2A 2399/4885ATM 4681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.