SCHEMBL28933285

SCHEMBL28933285

O=C(O)CON1C(=O)CCC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.42
TSHR P16473 3/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
PARL Q9H300 1/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
CTH P32929 1/20 0.33
CBS P35520 1/20 0.33
THPO P40225 1/20 0.33
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
ALOX15 P16050 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13479718 0.80 ALOX12 (0.37) ALOX12KMT2AATMALDH1A1CYP1A2
SCHEMBL3043213 0.78 ALOX12 (0.47) ALOX12TSHRKMT2AATMPARL
SCHEMBL18969713 0.78 ALOX12 (0.36) ALOX12TSHRKMT2ASMN1; SMN2MAPK1
SCHEMBL11502429 0.78 POLB (0.48) ALOX12KMT2AALDH1A1CYP2C9SMN1; SMN2
SCHEMBL28511791 0.75 ALOX12 (0.53) ALOX12TSHRKMT2AALDH1A1SMN1; SMN2
SCHEMBL28141243 0.75 KMT2A (0.33) ALOX12TSHRKMT2AATMPARL
SCHEMBL25763807 0.75 ALDH1A1 (0.66) ALOX12KMT2APARLALDH1A1CYP1A2
SCHEMBL263555 0.74 ALOX12 (0.36) ALOX12KMT2AATMSMN1; SMN2MAPK1
SCHEMBL10415663 0.74 CASP1 (0.38) TSHRKMT2ACTHCBSTHPO
SCHEMBL24153334 0.74 KMT2A (0.34) ALOX12KMT2AATMKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600657-B2 Rotary batch preheater ALEXANDER JEFFREY C (US) 2026-04-14 US disclosed
US-20260084995-A1 Rotary Batch Preheater ALEXANDER JEFFREY C (US) 2026-03-26 US disclosed
CN-115869456-B Preparation of in-situ gelation anti-swelling reinforced tissue adhesive material 上海其胜生物制剂有限公司 2024-12-27 CN disclosed
US-20240383792-A1 ROTARY BATCH AND CULLET PREHEATER SYSTEM AND METHOD ALEXANDER JEFFREY C (US) 2024-11-21 US disclosed
US-12084375-B2 Rotary batch and cullet preheater system and method ALEXANDER JEFFREY C (US) 2024-09-10 US disclosed
CN-117462693-A XTEN conjugate compositions and methods of making the same 阿穆尼克斯运营公司 2024-01-30 CN disclosed
CN-114621903-B Degradation strain for treating medical wastewater and application of degradation strain in bio-enhancement treatment 江苏聚庚科技股份有限公司 2023-10-13 CN disclosed
CN-116621964-A Method for preparing human thrombopoietin and human thrombopoietin 北京康禾科创生物科技开发有限公司 2023-08-22 CN disclosed
CN-115869456-A Preparation of in-situ gelation anti-swelling enhanced tissue adhesive material 上海其胜生物制剂有限公司 2023-03-31 CN disclosed
US-11590185-B2 Antioxidant composition comprising Sargassum serratifolium extract or fraction thereof as active ingredient PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY CORPORATION FOUNDATION (KR) 2023-02-28 US disclosed
US-20230038523-A1 Rotary Batch And Cullet Preheater System And Method ALEXANDER JEFFREY C (US) 2023-02-09 US disclosed
US-20230040599-A1 Rotary Batch Preheater ALEXANDER JEFFREY C (US) 2023-02-09 US disclosed
EP-4129935-A2 ROTARY BATCH AND CULLET PREHEATER SYSTEM AND METHOD Alexander, Jeffrey C. (US) 2023-02-08 EP disclosed
EP-4129934-A1 ROTARY BATCH PREHEATER Alexander, Jeffrey C. (US) 2023-02-08 EP disclosed
CN-114306722-B Injectable hydrogel type biological adhesive and preparation and application thereof 华东理工大学 2022-12-30 CN disclosed
CN-113030308-B Detection method of sulfonamide antibiotics in biogas slurry and sample treatment method thereof 浙江省农业科学院 2022-10-28 CN disclosed
CN-114621903-A Degradation strain for treating medical wastewater and application thereof in biological enhancement treatment 江苏聚庚科技有限公司 2022-06-14 CN disclosed
CN-114522225-A Arginine deiminase with reduced cross-reactivity to ADI-PEG20 antibodies for cancer treatment 瑞华药业集团 2022-05-24 CN disclosed
CN-114306722-A Injectable hydrogel type biological adhesive and preparation and application thereof 华东理工大学 2022-04-12 CN disclosed
CN-107073085-B Arginine deiminase with reduced cross-reactivity to ADI-PEG20 antibodies for cancer treatment 瑞华药业集团 2022-02-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600657-B2 Rotary batch preheater CRH, CUL5, CUL3 ALOX12 4291/4885TSHR 938/4885KMT2A 4623/4885
US-11590185-B2 Antioxidant composition comprising Sargassum serratifolium extract or fraction thereof as active ingredient GPX4, GPX1, CAT ALOX12 89/4885TSHR 3822/4885KMT2A 4210/4885
US-20260084995-A1 Rotary Batch Preheater ATP5F1A, ATP5F1B, ATP5F1C ALOX12 4502/4885TSHR 2219/4885KMT2A 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.