Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349558 | 0.82 | RECQL (0.57) | RECQLLOXLOXL3LOXL2NR3C2 | |
| SCHEMBL29459538 | 0.79 | TAAR1 (0.60) | TAAR1LTA4HIDO1DAOALDH1A1 | |
| SCHEMBL30000562 | 0.79 | TAAR1 (0.60) | TAAR1LTA4HIDO1DAOALDH1A1 | |
| SCHEMBL1263547 | 0.79 | TAAR1 (0.60) | TAAR1LTA4HIDO1DAOALDH1A1 | |
| SCHEMBL27160513 | 0.79 | RECQL (0.46) | RECQLLOXLOXL3LOXL2CYP2C19 | |
| SCHEMBL31288127 | 0.79 | HTR1B (0.50) | RECQLLOXLOXL3LOXL2NR3C2 | |
| SCHEMBL27160473 | 0.79 | RECQL (0.46) | RECQLLOXLOXL3LOXL2MAPK14 | |
| SCHEMBL11539964 | 0.78 | LTA4H (0.49) | NR3C2CYP3A4TAAR1LTA4HIDO1 | |
| SCHEMBL25177952 | 0.77 | TAAR1 (0.43) | NR3C2CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27160505 | 0.76 | RECQL (0.44) | RECQLLOXLOXL3LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773065-B2 | Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773065-B2 | Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists | GPR52, GPR68, GPR65 | RECQL 4518/4885LOX 3173/4885LOXL3 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.