SCHEMBL263601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL263822	0.89	ATM (0.55)	LMNAHPGDALDH1A1USP2MAPK1
	SCHEMBL263457	0.84	CYP3A4 (0.60)	LMNAALDH1A1GAAPOLBKMT2A
	SCHEMBL263931	0.80	CYP3A4 (0.61)	LMNAALDH1A1POLBSMN1; SMN2TSHR
	SCHEMBL264292	0.79	MAPT (0.62)	LMNAALDH1A1POLBKMT2AMEN1
	SCHEMBL14022735	0.78	HTR1A (0.53)	LMNAALDH1A1USP2MAPK1HTT
	SCHEMBL265216	0.78	CYP3A4 (0.54)	LMNAALDH1A1POLBKMT2AMEN1
	SCHEMBL14023515	0.77	MEN1 (0.51)	GAAPOLBKMT2AMEN1TSHR
	SCHEMBL17211747	0.73	LMNA (0.61)	LMNAHPGDBCAT2ALDH1A1USP2
	SCHEMBL264180	0.72	ALDH1A1 (0.79)	LMNAHPGDBCAT2ALDH1A1HTT
	SCHEMBL264298	0.71	USP2 (0.53)	LMNAHPGDBCAT2ALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.