SCHEMBL26366238

SCHEMBL26366238

CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OC[C@H]1O[C@@](C)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1cccc(C#N)c1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ P2RY10 O00398 4/20 0.33
▸ DNPH1 O43598 1/20 0.32
▸ POLRMT O00411 1/20 0.32
▸ GPR174 Q9BXC1 3/20 0.32
▸ ADK P55263 1/20 0.32
▸ GPR34 Q9UPC5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24305321 0.92 TMPRSS2 (0.37) P2RY10DNPH1POLRMTGPR174ADK
SCHEMBL29413326 0.92 TMPRSS2 (0.37) P2RY10DNPH1POLRMTGPR174ADK
SCHEMBL24304626 0.92 POLRMT (0.30) POLRMTADK
SCHEMBL25970656 0.91 ADK (0.37) POLRMTADK
SCHEMBL27455296 0.91 ADK (0.37) POLRMTADK
SCHEMBL25969534 0.91 ADK (0.37) POLRMTADK
SCHEMBL24304635 0.91 P2RY10 (0.31) P2RY10POLRMTADK
SCHEMBL25973621 0.91 P2RY10 (0.31) P2RY10POLRMTADK
SCHEMBL25969436 0.91 P2RY10 (0.31) P2RY10POLRMTADK
SCHEMBL25970036 0.91 P2RY10 (0.31) P2RY10POLRMTADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885DNPH1 2577/4885POLRMT 371/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885DNPH1 2577/4885POLRMT 371/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885DNPH1 2577/4885POLRMT 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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