SCHEMBL27455296

SCHEMBL27455296

CCCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OC[C@H]1O[C@@](C)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 4/20 0.37
▸ POLRMT O00411 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25969534 1.00 ADK (0.37) ADKPOLRMT
SCHEMBL25970656 1.00 ADK (0.37) ADKPOLRMT
SCHEMBL25970253 0.93 AKT1 (0.39) ADKPOLRMT
SCHEMBL25973720 0.93 AKT1 (0.39) ADKPOLRMT
SCHEMBL24407333 0.92 ADK (0.36) ADKPOLRMT
SCHEMBL25969778 0.92 ADK (0.36) ADKPOLRMT
SCHEMBL25969236 0.92 ADK (0.36) ADKPOLRMT
SCHEMBL25956838 0.91 ADK (0.35) ADKPOLRMT
SCHEMBL26366238 0.91 P2RY10 (0.33) ADKPOLRMT
SCHEMBL26366682 0.91 POLRMT (0.35) ADKPOLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885POLRMT 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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