Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637516 | 0.89 | MEN1 (0.48) | NPC1MEN1KMT2APDE2AKDM4E | |
| SCHEMBL2637180 | 0.89 | CGAS (0.46) | RAB9ANPC1MEN1PKMKMT2A | |
| SCHEMBL2638043 | 0.81 | MAPK10 (0.45) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL2637666 | 0.81 | POLB (0.43) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL2637350 | 0.80 | ERCC1 (0.48) | RAB9ANPC1MEN1PKMKMT2A | |
| SCHEMBL2637520 | 0.77 | DHODH (0.45) | RAB9ANPC1MEN1PKMKMT2A | |
| SCHEMBL2637918 | 0.76 | KMT2A (0.41) | RAB9ANPC1MEN1PKMKMT2A | |
| SCHEMBL2637908 | 0.75 | NPC1 (0.45) | RAB9ANPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2637592 | 0.74 | MEN1 (0.45) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL2637445 | 0.74 | NPC1 (0.38) | RAB9ANPC1MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |