Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637666 | 0.91 | POLB (0.43) | MEN1KMT2ARXFP1PIM1ROCK2 | |
| SCHEMBL2637515 | 0.89 | RAB9A (0.49) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2637180 | 0.86 | CGAS (0.46) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2638043 | 0.82 | MAPK10 (0.45) | MEN1KMT2AADORA2AADORA2BNPC1 | |
| SCHEMBL2637350 | 0.81 | ERCC1 (0.48) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2637204 | 0.81 | NPC1 (0.43) | MEN1KMT2AALDH1A1EGFRNPC1 | |
| SCHEMBL2637520 | 0.79 | DHODH (0.45) | MEN1KMT2AKDM4EEGFRSRC | |
| SCHEMBL2637918 | 0.78 | KMT2A (0.41) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2637908 | 0.77 | NPC1 (0.45) | MEN1KMT2AALDH1A1KDM4EADORA2A | |
| SCHEMBL2640983 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |