SCHEMBL18631920

SCHEMBL18631920

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(O)(C(=O)CCN)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.63
▸ CYP46A1 Q9Y6A2 2/20 0.63
▸ LMNA P02545 1/20 0.63
▸ ABCB1 P08183 1/20 0.63
▸ OSBP P22059 1/20 0.63
▸ RORC P51449 1/20 0.63
▸ OSBP2 Q969R2 1/20 0.63
▸ POLA1 P09884 1/20 0.59
▸ GRIN1 Q05586 10/20 0.58
▸ GRIN2B Q13224 10/20 0.58
▸ GRIN2A Q12879 8/20 0.57
▸ SRD5A1 P18405 3/20 0.56
▸ EPHA2 P29317 1/20 0.54
▸ NR1H3 Q13133 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318120 0.90 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2221515 0.90 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2637585 0.90 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.89 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.89 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.89 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.89 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.89 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194041 0.88 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194040 0.88 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114455-A1 RADIOSENSITIZING COMPOSITIONS AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH 2025-04-10 — — US disclosed
EP-4469057-A1 RADIOSENSITIZING COMPOSITIONS AND METHODS OF USE THEREOF University of Georgia Research Foundation, Inc. (US) 2024-12-04 — — EP disclosed
US-20240350662-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx (US) 2024-10-24 — — US disclosed
US-20240277740-A1 TREATMENT OF KNOWN AND UNKNOWN VIRAL INFECTION WITH LIPID AGENTS VIRATIDES, LLC 2024-08-22 — — US disclosed
US-20240156960-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT DNARx (US) 2024-05-16 — — US disclosed
US-20240033376-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx (US) 2024-02-01 — — US disclosed
CN-116615233-A Systems and methods for expressing biomolecules in a subject DNARX公司 2023-08-18 — — CN disclosed
WO-2023147552-A1 RADIOSENSITIZING COMPOSITIONS AND METHODS OF USE THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2023-08-03 — — WO disclosed
EP-4216935-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT Dnarx (US) 2023-08-02 — — EP disclosed
CN-116392609-A Systems and methods for in vivo nucleic acid expression DNARX公司 2023-07-07 — — CN disclosed
EP-3349730-B1 SYSTEMS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx (US) 2020-12-02 — — EP disclosed
EP-3600428-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO Dnarx (US) 2020-02-05 — — EP disclosed
US-20190083653-A1 Systems and Methods for Nucleic Acid Expression In Vivo DNARx 2019-03-21 — — US disclosed
US-20190046661-A1 Systems and Methods for Nucleic Acid Expression In Vivo DNARx 2019-02-14 — — US disclosed
US-20180280539-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx 2018-10-04 — — US disclosed
US-10086089-B2 Systems and methods for nucleic acid expression in vivo DNARx (US) 2018-10-02 — — US disclosed
WO-2018175932-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx (US) 2018-09-27 — — WO disclosed
EP-3349730-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO Dnarx (US) 2018-07-25 — — EP disclosed
US-20170080108-A1 Systems and Methods for Nucleic Acid Expression In Vivo DNARx 2017-03-23 — — US disclosed
WO-2017049132-A1 SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO DNARx (US) 2017-03-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114455-A1 RADIOSENSITIZING COMPOSITIONS AND METHODS OF USE THEREOF LIPA, DHCR7, LIPC USP2 1422/4885CYP46A1 42/4885LMNA 101/4885
US-20240156960-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT ACE2, ACE, IGF2BP2 USP2 260/4885CYP46A1 3363/4885LMNA 2261/4885
US-20240277740-A1 TREATMENT OF KNOWN AND UNKNOWN VIRAL INFECTION WITH LIPID AGENTS SPHK2, SGMS2, SPHK1 USP2 1831/4885CYP46A1 1701/4885LMNA 1816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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