Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25010849 | 0.82 | MAP3K12 (0.43) | MAP3K12JAK2 | |
| SCHEMBL69487 | 0.81 | MET (0.50) | MAP3K12 | |
| SCHEMBL21582516 | 0.81 | MAP3K12 (0.42) | MAP3K12JAK2 | |
| SCHEMBL10174184 | 0.81 | NOS3 (0.48) | MAP3K12 | |
| SCHEMBL16212144 | 0.79 | MAP3K12 (0.53) | MAP3K12 | |
| SCHEMBL27314054 | 0.78 | MAP3K12 (0.42) | MAP3K12 | |
| SCHEMBL10141672 | 0.78 | MAP3K12 (0.45) | MAP3K12 | |
| SCHEMBL19446253 | 0.77 | MAP3K12 (0.46) | MAP3K12 | |
| SCHEMBL26986690 | 0.77 | MET (0.53) | MAP3K12 | |
| SCHEMBL26917307 | 0.77 | MAP3K12 (0.41) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312473-A1 | PROCESS FOR THE PREPARATION OF BIHETEROARYL COMPOUNDS AND CRYSTAL FORMS THEREOF | GENENTECH, INC. (US) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312473-A1 | PROCESS FOR THE PREPARATION OF BIHETEROARYL COMPOUNDS AND CRYSTAL FORMS THEREOF | NONO, PNPO, KMO | MAP3K12 863/4885JAK2 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.