SCHEMBL26382000

SCHEMBL26382000

Cc1nc(Cl)nc2c1ncn2[C@H]1C[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHCY P23526 6/20 0.55
ADORA3 P0DMS8 9/20 0.50
ADORA1 P30542 4/20 0.45
ADORA2A P29274 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1908637 0.88 AHCY (0.55) AHCYADORA3ADORA1ADORA2A
SCHEMBL26381988 0.86 AHCY (0.57) AHCYADORA3ADORA1ADORA2A
SCHEMBL29501905 0.84 AHCY (0.73) AHCYADORA3ADORA1ADORA2A
SCHEMBL447258 0.84 AHCY (0.73) AHCYADORA3ADORA1ADORA2A
SCHEMBL19148493 0.83 YTHDC1 (0.46) ADORA3ADORA1ADORA2A
SCHEMBL26381995 0.80 AHCY (0.71) AHCYADORA3
SCHEMBL13177712 0.77 HTR2C (0.38) AHCYADORA3ADORA1ADORA2A
SCHEMBL8960194 0.76 AHCY (0.56) AHCYADORA3ADORA1ADORA2A
SCHEMBL12050237 0.76 AHCY (0.56) AHCYADORA3ADORA1ADORA2A
SCHEMBL26382100 0.74 AHCY (0.71) AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302003-A1 COMPOSITIONS AND METHODS FOR TREATING A CORONAVIRUS INFECTION ANTIRNA INCORPORATED 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302003-A1 COMPOSITIONS AND METHODS FOR TREATING A CORONAVIRUS INFECTION AHCY, AHCYL1, BHMT AHCY 1/4885ADORA3 931/4885ADORA1 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.