Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061281 | 0.78 | ALDH1A1 (0.40) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL16547534 | 0.78 | TDO2 (0.39) | TDP1LMNAMEN1GLAALDH1A1 | |
| SCHEMBL19975267 | 0.74 | PDE10A (0.34) | TDP1LMNAMEN1GLAALDH1A1 | |
| SCHEMBL16543457 | 0.74 | TRPV1 (0.38) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL24221966 | 0.74 | GABRA1 (0.42) | TDP1LMNAGLAALDH1A1PPARG | |
| SCHEMBL23228040 | 0.74 | ALDH1A1 (0.33) | TDP1LMNAGLAALDH1A1PPARG | |
| Hydrochloric Acid SCHEMBL19975461 | 0.73 | GABRA1 (0.41) | TDP1ALDH1A1HSD17B10TSHRNOS1 | |
| SCHEMBL3777154 | 0.73 | EGLN1 (0.51) | ALDH1A1PPARGMAPK10KMT2ANPSR1 | |
| SCHEMBL18320461 | 0.71 | ALDH1A1 (0.39) | TDP1LMNAALDH1A1PPARGMAPK10 | |
| SCHEMBL2529820 | 0.69 | FFAR4 (0.39) | LMNAMEN1ALDH1A1PPARGMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |