Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | TNKS | O95271 | 3/20 | 0.58 |
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.58 |
| ▸ | GUSB | P08236 | 7/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784145 | 0.81 | GUSB (0.73) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL874228 | 0.81 | GUSB (0.73) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL17710715 | 0.81 | RAB9A (0.60) | RAB9ANPC1 | |
| SCHEMBL8620410 | 0.80 | TNKS (0.83) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL11290144 | 0.78 | TNKS (0.61) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL16768506 | 0.78 | TNKS (0.78) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL259479 | 0.77 | ALDH1A1 (0.64) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL873906 | 0.77 | TNKS (0.71) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL17904243 | 0.77 | TNKS (0.71) | RAB9ANPC1TNKSPARP1TNKS2 | |
| SCHEMBL26120225 | 0.76 | CDK4 (0.56) | RAB9ANPC1TNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023187697-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-10-05 | — | — | WO | disclosed |