Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.56 |
| ▸ | CCND1 | P24385 | 3/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | BLK | P51451 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | STK3 | Q13188 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777039 | 0.80 | ROCK2 (0.63) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL26389177 | 0.79 | CYP1A2 (0.63) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL26118180 | 0.79 | ROCK2 (0.62) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL30634518 | 0.79 | ROCK2 (0.62) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL23587500 | 0.78 | ROCK2 (0.69) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL259479 | 0.77 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL29784145 | 0.77 | GUSB (0.73) | NPC1RAB9AGUSBTNKSPARP1 | |
| SCHEMBL874228 | 0.77 | GUSB (0.73) | NPC1RAB9AGUSBTNKSPARP1 | |
| SCHEMBL882944 | 0.77 | ROCK2 (0.77) | ROCK2CLK2BLKCSNK2A1STK3 | |
| SCHEMBL26389136 | 0.76 | RAB9A (0.72) | NPC1RAB9AGUSBTNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223279-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-07-10 | — | — | US | claimed |
| EP-4499600-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | Glenmark Life Sciences Limited (IN) | 2025-02-05 | — | — | EP | claimed |
| WO-2023187697-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-10-05 | — | — | WO | claimed |
| US-20250223279-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-07-10 | — | — | US | disclosed |
| EP-4499600-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | Glenmark Life Sciences Limited (IN) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023187697-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023187697-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250223279-A1 | PROCESS FOR THE PREPARATION OF BELUMOSUDIL MESYLATE AND ITS CRYSTALLINE FORM | ROCK1, PDE5A, SQLE | CDK4 1899/4885CCND1 3919/4885ROCK2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.