SCHEMBL2639637

SCHEMBL2639637

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nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 13/20 0.49
PTGS1 P23219 1/20 0.43
GSTK1 Q9Y2Q3 1/20 0.43
FOLH1 Q04609 2/20 0.41
GLO1 Q04760 1/20 0.41
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
GRIA4 P48058 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7641414 1.00 NOD1 (0.49) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL17627315 0.88 NOD1 (0.40) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL12599402 0.88 NOD1 (0.40) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL12599409 0.86 NOD1 (0.42) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL2640020 0.83 DPP4 (0.45) FOLH1GRM8GRM6GRIN2DGRIN3B
SCHEMBL20077204 0.82 NOD1 (0.55) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL20077214 0.82 NOD1 (0.55) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL22015678 0.80 NOD1 (0.52) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL22015849 0.80 NOD1 (0.56) NOD1PTGS1GSTK1FOLH1GLO1
SCHEMBL22015695 0.80 NOD1 (0.56) NOD1PTGS1GSTK1FOLH1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4787166-B2 2011-10-05 JP claimed
US-20080194492-A1 Plant Extracts for the Treatment of Incresed Bone Resorption UNIVERSITAT BERN (CH) 2008-08-14 US claimed
EP-1689422-A1 PLANT EXTRACTS FOR THE TREATMENT OF INCREASED BONE RESORPTION Universität Bern (CH) 2006-08-16 EP claimed
WO-2005051409-A1 PLANT EXTRACTS FOR THE TREATMENT OF INCREASED BONE RESORPTION Universität Bern (CH) 2005-06-09 WO claimed
CN-118903307-A Onion extract and preparation method and application thereof 宁波大学 2024-11-08 CN disclosed
CN-103214553-A Method for extracting onion osteogenic peptide LIAONING QIRUN BIOLOG TECHNOLOGY CO LTD 2013-07-24 CN disclosed
CN-101467690-A Nutritional composition containing five kinds of processed vegetable and fruit BIONTECH INC (CN) 2009-07-01 CN disclosed
WO-2009002371-A1 HEALTH-ENHANCING ETHNIC SALAD DRESSING MAGLIBA CECILLE R (US) 2008-12-31 WO disclosed
US-20080317936-A1 Health-enhancing ethnic salad dressing MAGLIBA CECILLE R 2008-12-25 US disclosed
US-20080194492-A1 Plant Extracts for the Treatment of Incresed Bone Resorption UNIVERSITAT BERN (CH) 2008-08-14 US disclosed
US-20080194492-A1 Plant Extracts for the Treatment of Incresed Bone Resorption UNIVERSITAT BERN (CH) 2008-08-14 US disclosed
EP-1689422-A1 PLANT EXTRACTS FOR THE TREATMENT OF INCREASED BONE RESORPTION Universität Bern (CH) 2006-08-16 EP disclosed
WO-2005051409-A1 PLANT EXTRACTS FOR THE TREATMENT OF INCREASED BONE RESORPTION Universität Bern (CH) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194492-A1 Plant Extracts for the Treatment of Incresed Bone Resorption GGCT, GGT1, GSS NOD1 2475/4885PTGS1 362/4885GSTK1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.