Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290777 | 0.85 | TSHR (0.77) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL381019 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TDP1L3MBTL1RAB9ATSHR | |
| SCHEMBL9096992 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL20506827 | 0.80 | TSHR (0.71) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL31205771 | 0.80 | TSHR (0.71) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL15623966 | 0.80 | TSHR (0.50) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL27095798 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL112400 | 0.79 | TDP1 (0.70) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL29626023 | 0.79 | TDP1 (0.70) | ALDH1A1TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL901184 | 0.79 | TDP1 (0.70) | ALDH1A1TDP1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4791634-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| EP-1169292-B1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | FIRMENICH & CIE (CH) | 2004-11-24 | — | — | EP | claimed |
| US-6589921-B2 | Such as 3,7-dimethyl-6-octenyl-2-formylbenzoate for after-shave lotion, cosmetics, soaps, shampoo/conditioners, other hair care products, bath/shower gels, foam baths, deodorants, air fresheners, detergents, or fabric softener | FIRMENICH SA (CH) | 2003-07-08 | — | — | US | claimed |
| US-20020169087-A1 | Cyclic compounds and their use as precursors of fragrant alcohols | FIRMENICH S.A | 2002-11-14 | — | — | US | claimed |
| US-20020032132-A1 | Cyclic compounds and their use as precursors of fragrant alcohols | ANTARES CAPITAL CORPORATION, AS AGENT | 2002-03-14 | — | — | US | claimed |
| EP-1169292-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | Firmenich S.A. (CH) | 2002-01-09 | — | — | EP | claimed |
| WO-2000058260-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | FIRMENICH S.A. (CH) | 2000-10-05 | — | — | WO | claimed |
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| US-10919869-B2 | Thiazole derivative and applications | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-02-16 | — | — | US | disclosed |
| US-20190292162-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| US-20020032132-A1 | Cyclic compounds and their use as precursors of fragrant alcohols | ANTARES CAPITAL CORPORATION, AS AGENT | 2002-03-14 | — | — | US | disclosed |
| EP-1169292-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | Firmenich S.A. (CH) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058260-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | FIRMENICH S.A. (CH) | 2000-10-05 | — | — | WO | disclosed |
| EP-0526529-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED INDOLONE DERIVATIVES | SMITH KLINE FRENCH LAB (GB) | 1996-10-16 | — | — | EP | disclosed |
| US-5336781-A | Process | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1994-08-09 | — | — | US | disclosed |
| EP-0526529-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED INDOLONE DERIVATIVES. | SMITH KLINE FRENCH LAB (GB) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991016306-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED INDOLONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | FABP2, SLC10A2, ALPI | ALDH1A1 63/4885TDP1 4479/4885L3MBTL1 4882/4885 |
| US-20190292162-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | DHODH, DLD, THOC2 | ALDH1A1 30/4885TDP1 1937/4885L3MBTL1 4730/4885 |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | ALDH1A1 63/4885TDP1 4479/4885L3MBTL1 4882/4885 |
| US-10919869-B2 | Thiazole derivative and applications | DHODH, DLD, THOC2 | ALDH1A1 30/4885TDP1 1937/4885L3MBTL1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.