Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625926 | 0.90 | TDP1 (0.55) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL28367951 | 0.88 | TDP1 (0.60) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL6322994 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL1897802 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL29878507 | 0.84 | TDP1 (0.56) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL6953191 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL2639728 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TDP1KMT2AL3MBTL1TSHR | |
| SCHEMBL50441 | 0.84 | ALDH1A1 (0.89) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL29388715 | 0.84 | ALDH1A1 (0.89) | ALDH1A1TDP1POLBSLC6A2SLC6A3 | |
| SCHEMBL13623068 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TDP1POLBSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4791634-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| US-6589921-B2 | Such as 3,7-dimethyl-6-octenyl-2-formylbenzoate for after-shave lotion, cosmetics, soaps, shampoo/conditioners, other hair care products, bath/shower gels, foam baths, deodorants, air fresheners, detergents, or fabric softener | FIRMENICH SA (CH) | 2003-07-08 | — | — | US | claimed |
| US-20020169087-A1 | Cyclic compounds and their use as precursors of fragrant alcohols | FIRMENICH S.A | 2002-11-14 | — | — | US | claimed |
| US-20020032132-A1 | Cyclic compounds and their use as precursors of fragrant alcohols | ANTARES CAPITAL CORPORATION, AS AGENT | 2002-03-14 | — | — | US | claimed |
| EP-1169292-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | Firmenich S.A. (CH) | 2002-01-09 | — | — | EP | claimed |
| WO-2000058260-A1 | CYCLIC COMPOUNDS AND THEIR USE AS PRECURSORS OF FRAGRANT ALCOHOLS | FIRMENICH S.A. (CH) | 2000-10-05 | — | — | WO | claimed |
| EP-0075629-A1 | Imidazole derivatives, their preparation, and their pharmaceutical compositions | Sumitomo Chemical Industries Ltd. (JP) | 1983-04-06 | — | — | EP | claimed |
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| US-10919869-B2 | Thiazole derivative and applications | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-02-16 | — | — | US | disclosed |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| US-20190292162-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
| EP-3459937-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | East China University of Science and Technology (CN) | 2019-03-27 | — | — | EP | disclosed |
| WO-1987007270-A1 | 1-CARBOALKOXYALKYL-3-ALKOXY-4-(2'-CARBOXYPHENYL)-AZET-2-ONES AS PLANT GROWTH REGULATORS AND SELECTIVE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4238507-A | ALPHA-AMINO-ALPHA-(3-HYDROXY-4-FORMYL-OR 4-HYDROXYMETHYLPHENYL) ACETIC ACID | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-12-09 | — | — | US | disclosed |
| US-4105781-A | ANTIALLERGENS FOR TREATMENT OF ASTHMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
| US-4049664-A | ANTIALLERGENS, ANTIASTHMATICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-09-20 | — | — | US | disclosed |
| US-3965122-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | FABP2, SLC10A2, ALPI | ALDH1A1 63/4885TDP1 4479/4885POLB 4458/4885 |
| US-20190292162-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | DHODH, DLD, THOC2 | ALDH1A1 30/4885TDP1 1937/4885POLB 4054/4885 |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | ALDH1A1 63/4885TDP1 4479/4885POLB 4458/4885 |
| US-10919869-B2 | Thiazole derivative and applications | DHODH, DLD, THOC2 | ALDH1A1 30/4885TDP1 1937/4885POLB 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.