Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640061 | 1.00 | TK1 (0.39) | TK1GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL9284740 | 0.80 | TK1 (0.60) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL2640245 | 0.80 | PYGM (0.52) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL8966491 | 0.80 | LMNA (0.57) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| 4'-Thiothymidine SCHEMBL23897630 | 0.80 | TK1 (0.49) | TK1LMNAADRA1ABLM | |
| 4'-Thiothymidine SCHEMBL23897578 | 0.80 | TK1 (0.49) | TK1LMNAADRA1ABLM | |
| SCHEMBL3691195 | 0.80 | TK1 (0.60) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| 4'-Thiothymidine SCHEMBL1942500 | 0.80 | TK1 (0.49) | TK1LMNAADRA1ABLM | |
| SCHEMBL2638724 | 0.80 | TK1 (0.41) | TK1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL8997855 | 0.80 | PYGM (0.52) | TK1LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08504753-A | — | — | 1996-05-21 | — | — | JP | claimed |
| EP-0421777-B1 | Further antiviral pyrimidine nucleosides | UNIV BIRMINGHAM (GB) | 1996-02-28 | — | — | EP | claimed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | claimed |
| WO-1994005686-A1 | ANOMERISATION PROCESS | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | claimed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | claimed |
| EP-0421777-A1 | Further antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-10 | — | — | EP | claimed |
| EP-0421777-B1 | Further antiviral pyrimidine nucleosides | UNIV BIRMINGHAM (GB) | 1996-02-28 | — | — | EP | disclosed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005686-A1 | ANOMERISATION PROCESS | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | disclosed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0421777-A1 | Further antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-10 | — | — | EP | disclosed |