Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26401235 | 0.81 | HDAC1 (0.41) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL9952763 | 0.78 | KCNQ3 (0.50) | HPGDNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL26038959 | 0.75 | CES1 (0.48) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL5371986 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKCNJ1P4HTMKDM4E | |
| SCHEMBL8364097 | 0.73 | P4HTM (0.48) | ALDH1A1HPGDP4HTMNPC1RAB9A | |
| SCHEMBL274958 | 0.71 | TTR (0.49) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL13534806 | 0.71 | CA12 (0.41) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL5696801 | 0.71 | NPC1 (0.59) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL9662948 | 0.70 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL13562370 | 0.70 | ALDH1A1 (0.40) | ALDH1A1HPGDKCNJ1P4HTMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779018-B2 | Heterocyclic compound and arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11779018-B2 | Heterocyclic compound and arthropod pest control composition containing same | C5, PRXL2A, NOX3 | ALDH1A1 2765/4885HPGD 3986/4885KCNJ1 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.