Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26404304 | 0.89 | HSD11B1 (0.34) | CXCR2GFERTSHRKDM4EHSD11B1 | |
| SCHEMBL26404229 | 0.87 | KDM4E (0.40) | TSHRKDM4EHSD11B1ALDH1A1LMNA | |
| SCHEMBL20339475 | 0.84 | HSD11B1 (0.34) | CXCR2KDM4EHSD11B1 | |
| SCHEMBL20340086 | 0.83 | HSD11B1 (0.33) | CXCR2GFERTSHRKDM4EHSD11B1 | |
| SCHEMBL26404230 | 0.80 | ALDH1A1 (0.56) | TSHRKDM4EALDH1A1LMNAHTT | |
| SCHEMBL20339549 | 0.77 | HSD11B1 (0.34) | KDM4EHSD11B1 | |
| SCHEMBL32688034 | 0.76 | PDE9A (0.43) | CXCR2KDM4EHTT | |
| SCHEMBL26404316 | 0.75 | ALDH1A1 (0.46) | CXCR2GFERTSHRKDM4EHSD11B1 | |
| SCHEMBL20339450 | 0.74 | KDM4E (0.58) | TSHRKDM4EALDH1A1LMNAHTT | |
| SCHEMBL32688401 | 0.74 | POLB (0.37) | CXCR2GFERTSHRKDM4EHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780812-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ORSOBIO, INC. (US) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780812-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ALDH7A1, ACMSD, AMD1 | CXCR2 4197/4885GFER 1137/4885TSHR 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.