Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585829 | 0.86 | HCAR3 (0.63) | PTGESMEN1KMT2ATRPV1NPC1 | |
| SCHEMBL5234574 | 0.86 | HCAR3 (0.63) | PTGESMEN1KMT2ATRPV1NPC1 | |
| SCHEMBL5738920 | 0.85 | PTGES (0.59) | PTGESTRPV1NPC1RAB9AGAA | |
| SCHEMBL26405685 | 0.83 | ABL1 (0.54) | PTGESABL1SRCKMT2ANPC1 | |
| SCHEMBL31585832 | 0.83 | ABL1 (0.53) | PTGESABL1SRCNPC1RAB9A | |
| SCHEMBL8827562 | 0.82 | RAB9A (0.65) | ABL1SRCMEN1KMT2ANPC1 | |
| SCHEMBL6809933 | 0.82 | MTTP (0.61) | PTGESTRPV1DEGS1F10PTGS1 | |
| SCHEMBL26406559 | 0.81 | KMT2A (0.59) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL30416204 | 0.81 | DEGS1 (0.60) | PTGESTRPV1NPC1RAB9AGAA | |
| SCHEMBL22871247 | 0.81 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253367-A1 | NOVEL BENZAZEPINE SPIRO DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |