Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26405873 | 0.87 | RAB9A (0.60) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL26405853 | 0.85 | RAB9A (0.58) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL26405742 | 0.85 | PTGES (0.51) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL5232050 | 0.83 | RAB9A (0.71) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL26405848 | 0.81 | RAB9A (0.59) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL25143173 | 0.77 | NPC1 (0.74) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL31665320 | 0.77 | NPC1 (0.74) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL5235844 | 0.76 | HCAR3 (0.68) | RAB9ANPC1ALOX15HTTMAPK1 | |
| SCHEMBL30839276 | 0.75 | HPGD (0.61) | RAB9ANPC1TP53ALDH1A1HPGD | |
| SCHEMBL24103987 | 0.75 | HPGD (0.61) | RAB9ANPC1TP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4253367-A1 | NOVEL BENZAZEPINE SPIRO DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |