SCHEMBL26409703

SCHEMBL26409703

O=C(O)C1(OCc2ccccc2)COC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16057453 0.85 KMT2A (0.51) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL4036434 0.84 KMT2A (0.46) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL5176709 0.81 KMT2A (0.44) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL26409711 0.81 MEN1 (0.39) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL17541113 0.79 ALDH1A1 (0.42) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL31721388 0.76 MEN1 (0.40) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL4966883 0.74 ALDH1A1 (0.41) KMT2AMEN1SLC1A3SLC1A2SLC1A1
SCHEMBL28395029 0.74 TSHR (0.39) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL4038161 0.74 KMT2A (0.47) KMT2AMEN1NPSR1SLC1A3SLC1A2
SCHEMBL15130271 0.74 TSHR (0.39) KMT2AMEN1NPSR1SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313980-B1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC (CA) 2026-04-22 EP disclosed
EP-4685147-A2 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2026-01-28 EP disclosed
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2026-01-20 US disclosed
EP-4313980-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2024-02-07 EP disclosed
CN-117500802-A LACTIVICIN compounds, their preparation and their use as antibacterial agents 费多拉制药有限公司 2024-02-02 CN disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-13 US disclosed
WO-2022208356-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, LPO, CLSPN KMT2A 3645/4885MEN1 3298/4885NPSR1 2769/4885
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO KMT2A 4105/4885MEN1 1859/4885NPSR1 3704/4885
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, VIP, LPO KMT2A 4131/4885MEN1 1873/4885NPSR1 3684/4885
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO KMT2A 4131/4885MEN1 1873/4885NPSR1 3684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.