Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569317 | 1.00 | CYP19A1 (0.48) | CYP19A1HTR2CMEN1KMT2AUSP2 | |
| SCHEMBL28170631 | 0.80 | HCRTR1 (0.43) | HTR2CHSD11B1HTR2AHTR2B | |
| SCHEMBL27319090 | 0.78 | CYP19A1 (0.49) | CYP19A1HTR2CHTR6ALDH1A1KDM4E | |
| SCHEMBL4310679 | 0.77 | HTR2C (0.49) | CYP19A1HTR2CMEN1KMT2AUSP2 | |
| SCHEMBL5125493 | 0.77 | HTR2C (0.49) | CYP19A1HTR2CMEN1KMT2AUSP2 | |
| SCHEMBL13970596 | 0.76 | HTR6 (0.46) | CYP19A1HTR2CMEN1KMT2AUSP2 | |
| SCHEMBL6414970 | 0.75 | LDHA (0.43) | HTR2CHTR6ALDH1A1KDM4ERECQL | |
| SCHEMBL30758308 | 0.75 | ALDH1A1 (0.41) | CYP19A1HTR2CMEN1KMT2AHTR6 | |
| SCHEMBL16464388 | 0.74 | CYP19A1 (0.50) | CYP19A1HTR2CMEN1KMT2AUSP2 | |
| SCHEMBL29041073 | 0.74 | HTR2C (0.51) | CYP19A1HTR2CMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |