Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408044 | 0.93 | CACNA1H (0.48) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26408046 | 0.85 | CACNA1H (0.46) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26408958 | 0.83 | GRM4 (0.41) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26409707 | 0.83 | GRM4 (0.43) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26408705 | 0.82 | NPSR1 (0.40) | CACNA1HKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL26409922 | 0.82 | CACNA1H (0.48) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26410807 | 0.81 | CACNA1H (0.41) | CACNA1HGRM4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL26409305 | 0.81 | CACNA1H (0.42) | CACNA1HKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL26408685 | 0.80 | TP53 (0.44) | KMT2AALDH1A1POLBMGLL | |
| SCHEMBL26409917 | 0.80 | GRM4 (0.47) | GRM4KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |