Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408044 | 0.89 | CACNA1H (0.48) | CACNA1HMEN1KMT2AALDH1A1FFAR4 | |
| SCHEMBL26408251 | 0.88 | CACNA1H (0.43) | LMNACACNA1HACKR3ALDH1A1KDM4E | |
| SCHEMBL26408701 | 0.87 | NPSR1 (0.49) | NPSR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26407873 | 0.86 | ACKR3 (0.44) | NPSR1LMNACACNA1HPOLBRXFP1 | |
| SCHEMBL26408706 | 0.85 | CACNA1H (0.36) | CACNA1HPOLBKDRFFAR4 | |
| SCHEMBL26408263 | 0.85 | CACNA1H (0.42) | LMNACACNA1HACKR3MEN1KMT2A | |
| SCHEMBL26408948 | 0.84 | SIGMAR1 (0.47) | CACNA1HPOLBDRD4 | |
| SCHEMBL26411550 | 0.82 | CACNA1H (0.42) | CACNA1HPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL26408707 | 0.81 | MGLL (0.43) | LMNACACNA1HMEN1KMT2AALDH1A1 | |
| SCHEMBL26408939 | 0.81 | NPY5R (0.43) | KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |