Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704670 | 0.91 | EPHX1 (0.37) | EPHX1ACHECYP1A2 | |
| SCHEMBL1205899 | 0.86 | EPHX1 (0.40) | EPHX1ACHECYP1A2 | |
| SCHEMBL27972821 | 0.84 | ACHE (0.32) | ACHE | |
| SCHEMBL27684736 | 0.84 | EPHX1 (0.43) | EPHX1ACHE | |
| SCHEMBL29104752 | 0.84 | ACHE (0.32) | ACHE | |
| SCHEMBL28656034 | 0.84 | ACHE (0.32) | ACHE | |
| SCHEMBL28056747 | 0.84 | EPHX1 (0.43) | EPHX1ACHE | |
| SCHEMBL31425438 | 0.84 | ACHE (0.32) | ACHE | |
| Hydrochloric Acid SCHEMBL27247810 | 0.83 | EPHX1 (0.42) | EPHX1ACHE | |
| SCHEMBL28837511 | 0.81 | TLR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190302026-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | WOOLEY KAREN L (US) | 2019-10-03 | — | — | US | disclosed |
| US-20180335385-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | THE WASHINGTON UNIVERSITY | 2018-11-22 | — | — | US | disclosed |
| US-9662387-B2 | Functional, cross-linked nanostructures for tandem optical imaging and therapy | MALLINCKRODT LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160256550-A1 | FUNCTIONAL, CROSS-LINKED NANOSTRUCTURES FOR TANDEM OPTICAL IMAGING AND THERAPY | MALLINCKRODT LLC (US) | 2016-09-08 | — | — | US | disclosed |
| US-9295650-B2 | Functional, cross-linked nanostructures for tandem optical imaging and therapy | MALLINCKRODT LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150346099-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | WOOLEY KAREN L (US) | 2015-12-03 | — | — | US | disclosed |
| US-20130210156-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | THE TEXAS A&M UNIVERSITY SYSTEM | 2013-08-15 | — | — | US | disclosed |
| US-20130137976-A1 | Functional, Cross-Linked Nanostructures for Tandem Optical Imaging and Therapy | IKARIA THERAPEUTICS LLC | 2013-05-30 | — | — | US | disclosed |
| WO-2011143540-A1 | UNIFORM, FUNCTIONALIZED, CROSS-LINKED NANOSTRUCTURES FOR MONITORING pH | MALLINCKRODT LLC (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256550-A1 | FUNCTIONAL, CROSS-LINKED NANOSTRUCTURES FOR TANDEM OPTICAL IMAGING AND THERAPY | MTCL3, EPHA2, UACA | EPHX1 567/4885ACHE 467/4885CYP1A2 4504/4885 |
| US-20190302026-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | MUC1, CD44, PFN1 | EPHX1 238/4885ACHE 435/4885CYP1A2 4268/4885 |
| US-20130137976-A1 | Functional, Cross-Linked Nanostructures for Tandem Optical Imaging and Therapy | MTCL3, EPHA2, UACA | EPHX1 567/4885ACHE 467/4885CYP1A2 4504/4885 |
| US-20180335385-A1 | Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH | MUC1, CD44, PFN1 | EPHX1 238/4885ACHE 435/4885CYP1A2 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.