SCHEMBL26415718

SCHEMBL26415718

CC(C)c1ccc2c(-c3cccc4c3oc3ccccc34)cccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
PRKDC P78527 5/20 0.40
TNKS O95271 1/20 0.40
PARP1 P09874 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CB P42338 1/20 0.39
NQO1 P15559 2/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
KIF11 P52732 1/20 0.37
HDAC8 Q9BY41 1/20 0.36
CYP2C9 P11712 1/20 0.36
CRHBP P24387 1/20 0.36
CASP7 P55210 1/20 0.36
CASP6 P55212 1/20 0.36
CRHR2 Q13324 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26415716 0.90 ALOX5 (0.49) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL24501848 0.90 ALOX5 (0.43) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL26416358 0.89 ALOX5 (0.48) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL26496136 0.88 ALOX5 (0.43) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL9916156 0.86 ALOX5 (0.53) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL26415765 0.85 AKR1C3 (0.39) PRKDCTNKSPARP1TNKS2HDAC6
SCHEMBL26415710 0.84 ALOX5 (0.44) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL22157994 0.83 ALOX5 (0.40) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL26415737 0.83 ALOX5 (0.56) ALOX5PRKDCTNKSPARP1TNKS2
SCHEMBL24502088 0.82 ALOX5 (0.43) ALOX5PRKDCTNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, MAOB, AOC2 ALOX5 587/4885PRKDC 3657/4885TNKS 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.