SCHEMBL26496136

SCHEMBL26496136

CC(C)c1ccc2oc3c(-c4cccc5ccccc45)cccc3c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
TNKS O95271 1/20 0.38
PARP1 P09874 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
TBK1 Q9UHD2 2/20 0.38
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CRHR1 P34998 1/20 0.36
PRKDC P78527 2/20 0.36
PIM1 P11309 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26416358 0.90 ALOX5 (0.48) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL24501848 0.89 ALOX5 (0.43) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL26415718 0.88 ALOX5 (0.48) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL26496117 0.85 ALOX5 (0.48) ALOX5AKR1C3AKR1C2TNKSPARP1
SCHEMBL24502102 0.84 ALOX5 (0.46) ALOX5TNKSPARP1TNKS2HDAC6
SCHEMBL23776004 0.84 TBK1 (0.46) MAOBTNKSPARP1TNKS2HDAC6
SCHEMBL24502088 0.83 ALOX5 (0.43) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL24502172 0.83 MAOA (0.42) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL24502175 0.83 TNKS (0.44) ALOX5MAOAMAOBAKR1C3AKR1C2
SCHEMBL25775078 0.81 MAOA (0.58) ALOX5MAOAMAOBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136831-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-04 US disclosed
US-20230136831-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-04 US disclosed