Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975654 | 0.90 | ASIC3 (0.53) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| SCHEMBL22134624 | 0.81 | ASIC3 (0.44) | ASIC3LOXL2HTR1AHTR7PDCD1 | |
| SCHEMBL18790907 | 0.78 | ASIC3 (0.47) | ASIC3HTR1AHTR7WNT3ASREBF2 | |
| SCHEMBL10271516 | 0.78 | ASIC3 (0.53) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| Hydrochloric Acid SCHEMBL28148503 | 0.76 | ASIC3 (0.52) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| SCHEMBL22134626 | 0.76 | PDCD1 (0.42) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| SCHEMBL26172508 | 0.75 | LOXL2 (0.41) | ASIC3LOXL2KDM4EALDH1A1SREBF2 | |
| SCHEMBL12369304 | 0.75 | ASIC3 (0.47) | ASIC3LOXL2HTR1AHTR7FFAR1 | |
| SCHEMBL18625006 | 0.75 | ASIC3 (0.47) | ASIC3HTR1AHTR7FFAR1CYP11B1 | |
| SCHEMBL12747271 | 0.75 | CCR1 (0.43) | LOXL2NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | ASIC3 154/4885LOXL2 4362/4885HTR1A 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.