Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816500 | 0.85 | DRD2 (0.48) | ALDH1A1ALDH1A3HTR1AL3MBTL1SMN1; SMN2 | |
| SCHEMBL16440156 | 0.83 | ALDH1A1 (0.44) | ALDH1A1ALDH1A3ACHEHTR1AHTR3A | |
| SCHEMBL16440159 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ACHEHTR1AHTR3A | |
| SCHEMBL24123755 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ACHESUV39H2HTR1A | |
| SCHEMBL12362773 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ACHESUV39H2HTR1A | |
| SCHEMBL25678409 | 0.82 | MEN1 (0.40) | ALDH1A1ALDH1A3SUV39H2HTR1ALMNA | |
| SCHEMBL24123767 | 0.81 | MAPT (0.47) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL26407207 | 0.81 | OPRK1 (0.43) | ALDH1A1ALDH1A3SUV39H2LMNAHTT | |
| SCHEMBL8693688 | 0.80 | DRD2 (0.58) | ALDH1A1HTR3ALMNADRD2ADRA1D | |
| SCHEMBL22547420 | 0.79 | KCNH2 (0.48) | ALDH1A1ALDH1A3ACHESUV39H2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |