Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 11/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641796 | 0.86 | MAPT (0.51) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641800 | 0.86 | MAPT (0.51) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL12186010 | 0.84 | PAX8 (0.41) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641861 | 0.80 | RAB9A (0.41) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641930 | 0.80 | RAB9A (0.41) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641792 | 0.80 | EGFR (0.43) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641896 | 0.80 | RAB9A (0.41) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL2641830 | 0.79 | BACE1 (0.40) | MAPTSMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL2641871 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL11479535 | 0.76 | NFE2L2 (0.57) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |