Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641800 | 1.00 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641783 | 0.86 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL11479540 | 0.81 | NFE2L2 (0.57) | MAPTSMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL11479535 | 0.81 | NFE2L2 (0.57) | MAPTSMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL12186010 | 0.80 | PAX8 (0.41) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL9000446 | 0.76 | KMT2A (0.41) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641858 | 0.75 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641851 | 0.75 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641832 | 0.75 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2641926 | 0.75 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |