Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641825 | 1.00 | NFE2L2 (0.51) | NFE2L2MAPTKDRRELAESR1 | |
| SCHEMBL2641846 | 0.85 | NFE2L2 (0.67) | NFE2L2MAPTRELAESR1AHR | |
| SCHEMBL2641840 | 0.85 | NFE2L2 (0.67) | NFE2L2MAPTRELAESR1AHR | |
| SCHEMBL4693722 | 0.84 | RELA (0.53) | NFE2L2MAPTRELAESR1AHR | |
| SCHEMBL4693719 | 0.84 | RELA (0.53) | NFE2L2MAPTRELAESR1AHR | |
| SCHEMBL12567393 | 0.84 | RELA (0.53) | NFE2L2MAPTRELAESR1AHR | |
| SCHEMBL29965553 | 0.83 | CHRNB2 (0.44) | NFE2L2 | |
| SCHEMBL595487 | 0.83 | CHRNB2 (0.44) | NFE2L2 | |
| SCHEMBL12567390 | 0.76 | CHRNA7 (0.47) | MAPTKDRRELAESR1AHR | |
| SCHEMBL12203894 | 0.75 | ALDH1A1 (0.61) | MAPTKDRRELAESR1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |