Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 18/20 | 0.49 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641860 | 1.00 | KCNH2 (0.50) | KCNH2APPMAT2AMAPTSNCA | |
| SCHEMBL7970830 | 0.82 | LOXL2 (0.45) | MAPT | |
| SCHEMBL7970832 | 0.82 | LOXL2 (0.45) | MAPT | |
| SCHEMBL2879571 | 0.80 | NFE2L2 (0.52) | APP | |
| SCHEMBL2879570 | 0.80 | NFE2L2 (0.52) | APP | |
| SCHEMBL12185927 | 0.77 | KDM1A (0.55) | APPMAPT | |
| SCHEMBL12185880 | 0.77 | NQO2 (0.50) | APPMAPT | |
| SCHEMBL2641826 | 0.77 | CYP1A2 (0.61) | MAPT | |
| SCHEMBL12186016 | 0.77 | MAPT (0.61) | KCNH2APPMAT2AMAPT | |
| SCHEMBL2641818 | 0.77 | CYP1A2 (0.61) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |