Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | PGK1 | P00558 | 5/20 | 0.44 |
| ▸ | PGK2 | P07205 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915764 | 0.86 | ENPP2 (0.45) | ENPP2PGK1PGK2PTPN1S1PR2 | |
| SCHEMBL13640333 | 0.84 | MMP2 (0.36) | PTPN1CYP2C19SMN1; SMN2PTPRCPTPN2 | |
| SCHEMBL16301967 | 0.81 | NQO1 (0.54) | ENPP2PGK1PGK2PTPN1SMN1; SMN2 | |
| SCHEMBL31187555 | 0.81 | KDM4E (0.45) | ENPP2PGK1PGK2PTPN1SMN1; SMN2 | |
| SCHEMBL915653 | 0.81 | CYP1A2 (0.43) | ENPP2PGK1PGK2PTPN1CYP2C19 | |
| SCHEMBL915416 | 0.81 | CHEK2 (0.42) | ENPP2PGK1PGK2PTPN1S1PR2 | |
| SCHEMBL915789 | 0.81 | PTPN1 (0.51) | ENPP2PGK1PGK2PTPN1S1PR2 | |
| SCHEMBL914654 | 0.81 | ANPEP (0.53) | ENPP2PGK1PGK2ANPEPERAP2 | |
| SCHEMBL12082470 | 0.78 | CCNT1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL7314987 | 0.78 | PGK1 (0.50) | ENPP2PGK1PGK2PTPN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |