SCHEMBL26418711

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1874571	0.95	HDAC1 (0.56)	HDAC1HDAC2MMP3MMP2ALDH1A1
	Phenol SCHEMBL1877890	0.90	MMP2 (0.52)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL29321625	0.84	ALDH1A1 (0.49)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL29316111	0.84	ALDH1A1 (0.49)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL21078349	0.83	HTT (0.55)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL12676172	0.83	HDAC1 (0.50)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL8621621	0.83	NPC1 (0.63)	HDAC1HDAC2MMP3ALDH1A1MAPT
	SCHEMBL10054731	0.83	MMP2 (0.52)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL2993045	0.83	HRH2 (0.56)	HDAC1HDAC2MMP3MMP2ALDH1A1
	SCHEMBL3434932	0.83	NPC1 (0.63)	HDAC1HDAC2MMP3ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.