Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL1877890 | 0.95 | MMP2 (0.52) | HDAC1HDAC2MMP3LMNAESR1 | |
| SCHEMBL26418711 | 0.95 | HDAC1 (0.61) | HDAC1HDAC2MMP3MMP2ALDH1A1 | |
| SCHEMBL12670743 | 0.85 | MMP3 (0.53) | HDAC1HDAC2MMP3LMNASMN1; SMN2 | |
| SCHEMBL29266641 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2MMP3MMP2ALDH1A1 | |
| SCHEMBL29290457 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2MMP3MMP2ALDH1A1 | |
| SCHEMBL29266656 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2MMP3MMP2ALDH1A1 | |
| SCHEMBL29266684 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2MMP3MMP2ALDH1A1 | |
| SCHEMBL6393672 | 0.80 | POLB (0.62) | LMNAESR1CYP1A2CYP2D6TSHR | |
| SCHEMBL4575829 | 0.80 | TSHR (0.79) | LMNAESR1CYP1A2CYP2D6TSHR | |
| SCHEMBL29321625 | 0.80 | ALDH1A1 (0.49) | HDAC1HDAC2MMP3TSHRMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947802-B2 | Benzoxazine monomers, polymers and compositions | CASE WESTERN RESERVE UNIVERSITY (US) | 2011-05-24 | — | — | US | disclosed |
| US-20090069533-A1 | Benzoxazine monomers, polymers and compositions | CASE WESTERN RESERVE UNIVERSITY | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069533-A1 | Benzoxazine monomers, polymers and compositions | MUS81, DDX42, BRAP | HDAC1 2105/4885HDAC2 2894/4885MMP3 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.