SCHEMBL26420033

SCHEMBL26420033

Cc1cc(=O)n(-c2ccc(Cl)cc2F)c(=O)n1N1C(=O)c2ccccc2C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
SLC22A12 Q96S37 1/20 0.35
KMT2A Q03164 3/20 0.34
MYC P01106 1/20 0.34
NR4A1 P22736 1/20 0.34
APAF1 O14727 1/20 0.34
GLA P06280 1/20 0.34
SLC22A1 O15245 1/20 0.34
ABCB11 O95342 1/20 0.34
CYP3A4 P08684 1/20 0.34
DRD3 P35462 1/20 0.34
OPRK1 P41145 1/20 0.34
PDE4D Q08499 1/20 0.34
AOC3 Q16853 1/20 0.34
HSD11B1 P28845 2/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22520002 0.84 HSD11B1 (0.34) S1PR4S1PR1S1PR5SLC22A12KMT2A
SCHEMBL10575241 0.77 S1PR4 (0.42) S1PR4S1PR1S1PR5SLC22A12KMT2A
SCHEMBL26420035 0.76 S1PR4 (0.39) S1PR4S1PR1S1PR5SLC22A12MYC
SCHEMBL30273429 0.72 MEN1 (0.53) KMT2ACYP3A4MEN1ALDH1A1GAA
SCHEMBL7729256 0.72 MEN1 (0.53) KMT2ACYP3A4MEN1ALDH1A1GAA
SCHEMBL20575403 0.68 MYC (0.54) S1PR4S1PR1S1PR5SLC22A12KMT2A
SCHEMBL9375345 0.67 MAPK13 (0.43) KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11826010 0.66 MEN1 (0.46) KMT2ACYP3A4MEN1ALDH1A1GAA
SCHEMBL10574822 0.66 SMN1; SMN2 (0.61) S1PR4S1PR1S1PR5SLC22A12KMT2A
SCHEMBL29709206 0.66 HSD11B1 (0.36) S1PR4S1PR1S1PR5SLC22A12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131260-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS UNG, TYMP, TYMS S1PR4 4304/4885S1PR1 4065/4885S1PR5 4205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.