Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350794 | 0.84 | FGFR1 (0.62) | FGFR1HTTTHRBMAPTALDH1A1 | |
| SCHEMBL29623644 | 0.84 | FGFR1 (0.62) | FGFR1HTTTHRBMAPTALDH1A1 | |
| SCHEMBL11679463 | 0.83 | FGFR1 (0.66) | FGFR1HTTALDH1A1 | |
| SCHEMBL19848504 | 0.82 | ALDH1A1 (0.49) | FGFR1HTTTHRBMAPTALDH1A1 | |
| SCHEMBL3846616 | 0.82 | HCAR1 (0.49) | FGFR1HTTALDH1A1 | |
| SCHEMBL20603947 | 0.78 | FGFR1 (0.67) | FGFR1THRBSMN1; SMN2 | |
| SCHEMBL5246440 | 0.78 | HTT (0.75) | FGFR1HTTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31402983 | 0.77 | FGFR1 (0.71) | FGFR1THRBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20627475 | 0.77 | NPC1 (0.47) | FGFR1HTTTHRBMAPTALDH1A1 | |
| SCHEMBL28824907 | 0.76 | HTT (0.72) | FGFR1HTTMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |