Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376239 | 0.85 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL487226 | 0.78 | ENPP2 (0.56) | ENPP2PTGS2 | |
| SCHEMBL10300269 | 0.77 | PTGS2 (0.62) | ENPP2PTGS2KIF11 | |
| SCHEMBL7677302 | 0.77 | PTGS2 (0.62) | ENPP2PTGS2KIF11 | |
| SCHEMBL17548700 | 0.77 | ENPP2 (0.62) | ENPP2PTGS2 | |
| Water SCHEMBL22687010 | 0.76 | ENPP2 (0.54) | ENPP2PTGS2 | |
| Water SCHEMBL28883186 | 0.76 | ENPP2 (0.54) | ENPP2PTGS2 | |
| SCHEMBL517832 | 0.74 | ENPP2 (0.59) | ENPP2PTGS2 | |
| SCHEMBL12807 | 0.74 | GAA (0.65) | ENPP2PTGS2 | |
| SCHEMBL28182477 | 0.74 | GAA (0.65) | ENPP2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957487-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | claimed |
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2007-06-28 | — | — | US | claimed |
| WO-2007054556-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ÆTERNA ZENTARIS GMBH (DE) | 2007-05-18 | — | — | WO | claimed |
| EP-0073454-B1 | 6-ALPHA-METHOXY-PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1985-05-02 | — | — | EP | claimed |
| US-4454128-A | ANTIBIOTICS | DR. KARL THOMAE GMBH (DE) | 1984-06-12 | — | — | US | claimed |
| EP-0035161-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1983-11-23 | — | — | EP | claimed |
| EP-0073454-A2 | 6-Alpha-methoxy-penicillins, their salts, process for their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-03-09 | — | — | EP | claimed |
| US-4370327-A | Cephalosporins and pharmaceutical compositions | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-25 | — | — | US | claimed |
| EP-0035161-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds | Dr. Karl Thomae GmbH (DE) | 1981-09-09 | — | — | EP | claimed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130157976-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | CLAUS ECKHARD (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120252760-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | ZENTARIS GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| EP-0418743-A2 | Heat-developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |
| EP-0073454-B1 | 6-ALPHA-METHOXY-PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1985-05-02 | — | — | EP | disclosed |
| US-4454128-A | ANTIBIOTICS | DR. KARL THOMAE GMBH (DE) | 1984-06-12 | — | — | US | disclosed |
| EP-0035161-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4370327-A | Cephalosporins and pharmaceutical compositions | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| EP-0035161-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds | Dr. Karl Thomae GmbH (DE) | 1981-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149484-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | ENPP2 770/4885PTGS2 1036/4885KIF11 1584/4885 |
| US-20120252760-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | ENPP2 770/4885PTGS2 1036/4885KIF11 1584/4885 |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | ENPP2 1848/4885PTGS2 1350/4885KIF11 3957/4885 |
| US-20130157976-A1 | NOVEL PYRIDOPYRAZINES AND THEIR USE AS MODULATORS OF KINASES | MAP4K2, MAP3K15, MAP3K5 | ENPP2 770/4885PTGS2 1036/4885KIF11 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.