SCHEMBL26426129

SCHEMBL26426129

NC(=O)[C@H](Cc1ccccc1Cl)NC(=O)CCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MME P08473 9/20 0.46
CTSG P08311 1/20 0.46
CMA1 P23946 1/20 0.46
MMEL1 Q495T6 2/20 0.43
FOLH1 Q04609 1/20 0.43
ACE P12821 3/20 0.43
MMP2 P08253 1/20 0.42
MMP8 P22894 1/20 0.42
MMP12 P39900 1/20 0.42
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26425140 0.90 CTSG (0.52) MMECTSGCMA1MMEL1ACE
SCHEMBL26424830 0.85 MMEL1 (0.46) MMEMMEL1ACE
SCHEMBL26427643 0.82 HRH4 (0.48) MMEFOLH1ACEMMP8
SCHEMBL26425109 0.81 MME (0.56) MMEACE
SCHEMBL26424799 0.78 MMEL1 (0.47) MMEMMEL1FOLH1ACEFFAR1
SCHEMBL26424764 0.78 MME (0.60) MMEMMEL1ACE
SCHEMBL26424706 0.77 KMT2A (0.56) MMEMMEL1FOLH1ACEMMP2
SCHEMBL26426151 0.76 MME (0.45) MMEMMEL1ACEMMP2MMP8
SCHEMBL26412803 0.76 ECE1 (0.61) ACE
SCHEMBL28142230 0.73 PIN1 (0.51) MMECTSGCMA1FOLH1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed