Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 6/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159831 | 0.98 | HPGDS (0.42) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL22133062 | 0.98 | HPGDS (0.42) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL15302247 | 0.98 | HPGDS (0.42) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL32675730 | 0.88 | HPGDS (0.48) | HPGDSSLC6A5TLR2FOLH1NMT2 | |
| SCHEMBL5156017 | 0.88 | HPGDS (0.48) | HPGDSSLC6A5TLR2FOLH1NMT2 | |
| SCHEMBL24065513 | 0.88 | SIRT6 (0.42) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL16494812 | 0.88 | SLC6A5 (0.50) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL16494813 | 0.88 | SLC6A5 (0.50) | HPGDSSLC6A5TLR2F2FOLH1 | |
| SCHEMBL26426329 | 0.88 | QRFPR (0.42) | HPGDSTLR2QRFPRSIRT6SIRT1 | |
| SCHEMBL22674899 | 0.87 | FURIN (0.42) | TLR2QRFPRNMT2NMT1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286936-A1 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES | BRACCO SUISSE SA (CH) | 2011-11-24 | — | — | US | disclosed |