Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429016 | 0.81 | LMNA (0.35) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL26429018 | 0.79 | NPSR1 (0.34) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL26429017 | 0.78 | NPSR1 (0.33) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL25771035 | 0.77 | LMNA (0.47) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL25690687 | 0.76 | ABHD6 (0.44) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL20004202 | 0.73 | LMNA (0.39) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL2510973 | 0.73 | KMT2A (0.50) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL25939713 | 0.73 | LMNA (0.50) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL25770782 | 0.72 | F2 (0.41) | LMNAF2TSHRKMT2AMAPT | |
| SCHEMBL1249246 | 0.72 | HPGD (0.53) | LMNAF2TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |