Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429018 | 0.89 | NPSR1 (0.34) | NPSR1LMNAF2KMT2AMAPT | |
| SCHEMBL26429016 | 0.81 | LMNA (0.35) | NPSR1LMNAF2KMT2AMAPT | |
| SCHEMBL26429014 | 0.78 | LMNA (0.42) | NPSR1LMNAF2KMT2AMAPT | |
| SCHEMBL25690687 | 0.71 | ABHD6 (0.44) | NPSR1LMNAF2KMT2AMAPT | |
| SCHEMBL25771035 | 0.70 | LMNA (0.47) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL20004202 | 0.66 | LMNA (0.39) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL25939713 | 0.63 | LMNA (0.50) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL2510973 | 0.63 | KMT2A (0.50) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL25770782 | 0.62 | F2 (0.41) | LMNAF2KMT2AMAPTMEN1 | |
| SCHEMBL1115558 | 0.62 | OPRD1 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |