SCHEMBL26429408

SCHEMBL26429408

NCC(=O)NC(C=O)CCC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ PMP22 Q01453 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ DPP4 P27487 1/20 0.33
▸ DPP8 Q6V1X1 1/20 0.33
▸ DPP9 Q86TI2 1/20 0.33
▸ CTSK P43235 4/20 0.32
▸ BMP1 P13497 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26429181 1.00 ALOX15 (0.35) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL29140277 0.98 ALOX15 (0.34) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL29768848 0.85 CTSC (0.39) BLMKMT2A
SCHEMBL22731801 0.85 CTSC (0.39) BLMKMT2A
SCHEMBL16181956 0.85 CTSC (0.39) BLMKMT2A
SCHEMBL26429623 0.81 BMP1 (0.38) BMP1
SCHEMBL24943424 0.81 CTSK (0.33) CTSK
SCHEMBL11363519 0.79 DPP4 (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL22387766 0.79 CTSK (0.39) DPP4DPP8DPP9CTSK
SCHEMBL23656864 0.79 CTSK (0.33) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127524-A1 FILAMENTOUS NANOSTRUCTURES AND THEIR USE FOR TREATMENT OF PULMONARY DISEASE NATIONAL SCIENCE FOUNDATION 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127524-A1 FILAMENTOUS NANOSTRUCTURES AND THEIR USE FOR TREATMENT OF PULMONARY DISEASE MFAP1, DIAPH1, SEPTIN7 ALOX15 2891/4885BLM 276/4885PMP22 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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